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If you used "sudo" to install Firefox and it starts at the end of the install process and runs when you log in as root but fails to run as a normal user, then check the ownership of "$HOME/.mozilla" and subdirectories.The symptoms are that you won't get any error messages, and Firefox will exit with a value of 1.  If you see message, This application has failed to start because js3250was not found.Re-installing the application may fix this problem.If the problem persists, download the Firefox setup file from mozilla.org, remove the "Mozilla Firefox" program folder and then, with Zone Alarm Force Field turned off, reinstall Firefox.      If you see a message similar to Your computer must be restarted to complete a previous upgrade of Firefox after a major update (e.g., from Firefox 3.6 to 8.0) and restarting the computer doesn't help: On Windows, open the Mozilla Firefox installation directory (e.g., C:\Program Files\Mozilla Firefox or, on 64-bit Windows, C:\Program Files (x86)\Mozilla Firefox) and delete the file "moz-upgrade", if found.Alternately, do a clean reinstall (use another browser to download the Firefox installer from and, after first removing the Mozilla Firefox installation directory, reinstall Firefox).This Firefox startup error can occur after performing a Windows System Restore (bug 877143) but whatever the reason, the usual solution is to do a clean reinstall by removing the Firefox program folder and then reinstalling Firefox (there's normally no need to uninstall Firefox before reinstalling it):    This can be caused by an incorrect setting in the Windows registry.If you attempt to install the Opera browser as a workaround, or if you attempt to install or remove various Microsoft applications, you will see an error similar to, Error 1606: Could Not Access Network Location.
You should then delete the program folder for your Mozilla browser and run the installer you previously downloaded.
You may see an error message similar to: - Application Error. Internet Explorer, Google Chrome, or other browsers may also fail to start.
The instruction at “0x5a9288f8” referenced memory at “0x5a9288f8”. See if updating System Mechanic fixes the problem or, if don't need the program, consider uninstalling it.
This should allow Firefox to start but you will still need to update Firefox.
Updating Firefox may resolve the issue but if the problem persists, download the Firefox setup file from mozilla.org, remove the "Mozilla Firefox" program folder and then reinstall Firefox.If the browser starts when you run it in Safe Mode, it's likely that an extension or, in Firefox 4 and above, hardware acceleration is causing the problem.